Androgen receptor CAG polymorphism (Xq11-12) status and human spermatogenesis: A prospective analysis of infertile males and their offspring conceived by intracytoplasmic sperm injection

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Androgen receptor CAG polymorphism (Xq11-12) status and human spermatogenesis: a prospective analysis of infertile males and their offspring conceived by intracytoplasmic sperm injection.

We determined the association of androgen receptor (AR) (CAG)n lengths among fertile and infertile males and offspring conceived by intracytoplasmic sperm injection (ICSI). Assessment of (CAG)n repeats in the AR was performed in a Caucasian population by gene sequencing in fertile men (n=13), infertile men (n=64), boys conceived after ICSI (n=21), and boys conceived naturally (n=11). In the AZF...

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Birth defects in children conceived by in vitro fertilization and intracytoplasmic sperm injection: a meta-analysis.

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A prospective controlled study of karyotyping for 430 consecutive babies conceived through intracytoplasmic sperm injection.

OBJECTIVE To compare the karyotype of babies conceived through ICSI with that of naturally conceived babies. DESIGN Prospective controlled study. SETTING The Egyptian IVF-ET Center, Cairo, Egypt. PATIENT(S) Four hundred and thirty babies conceived through ICSI and 430 babies conceived naturally. INTERVENTION(S) ICSI and karyotyping. MAIN OUTCOME MEASURE(S) Abnormal karyotype. RESULT...

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Children Born After Intracytoplasmic Sperm Injection Compared with Spontaneously Conceived Children a Prospective Study

Objective: To study the outcome of ICSI conceived children in our IVF center; their growth, their psychomotor development and to find out possible birth defects and genetic anomalies. Material and Methods: This is a prospective survey about ICSI conceived children and naturally conceived children in our IVF center over the period between 2007 and 2012. One hundred ICSI children aged between 2 a...

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Androgen receptor polymorphism (CAG repeats) and androgenicity.

Objective Polymorphism of the androgen receptor (AR) has been related to various pathophysiological conditions, such as osteoporosis and infertility. The objectives of this study were to evaluate the frequency of distribution in a normal Italian population and to assess CAG repeats (CAGr) in other conditions, such as hypoandrogenism, potentially influenced by AR polymorphism. Patients and measu...

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ژورنال

عنوان ژورنال: International Journal of Molecular Medicine

سال: 2006

ISSN: 1107-3756,1791-244X

DOI: 10.3892/ijmm.18.3.405